Bon Secours St. Francis Health System announced plans for a new medical campus in the Powdersville area, aimed at expanding access to high-quality care for residents of northeastern Anderson County and surrounding communities.
The Bon Secours Powdersville Medical Center, located at 104 Roe Road in Greenville, officially broke ground on November 21st.
“Powdersville is one of the fastest-growing areas in our region, and we’re excited to meet the healthcare needs of this vibrant community,” said Matt Caldwell, president of Bon Secours St. Francis Health System. “This new campus reflects our commitment to providing convenient, comprehensive care close to home.”
The new site will feature a 40,000-square-foot medical office building housing a wide range of primary and specialty care services, including:
- Bon Secours Palmetto Greenville Urology – Powdersville
- Bon Secours Gastroenterology – Powdersville
- Bon Secours Carolina Surgical – Powdersville
- Bon Secours Carolina ENT – Powdersville
- Bon Secours Piedmont Orthopaedics – Powdersville
- Bon Secours OB-GYN – Powdersville
- Bon Secours Upstate Cardiology – Powdersville
- Bon Secours Hematology and Oncology – Powdersville (to include infusion services)
- Bon Secours Primary Care – Powdersville
Radiology and lab services will also be available at this location. In addition to the medical office building, the campus will include a freestanding emergency department (ED). Modeled after the facility Bon Secours will soon be opening in Five Forks, this 12,500-square-foot ED will feature 9 exam rooms, including one dedicated to trauma care, as well as CT and X-ray imaging. It will provide 24/7 access to board-certified emergency medicine professionals and state-of-the-art technology for a wide range of urgent medical needs.
“This is more than just a building. It’s a promise to our patients that we’re here for them, wherever they are,” said Caldwell. “We’re proud to bring the Bon Secours legacy of compassionate, high-quality care to Powdersville.”
The Bon Secours Powdersville Medical Campus is expected to open in early 2027. For more information about Bon Secours services, locations, and updates on the Powdersville project, visit bonsecours.com.
Bon Secours – Greenville
Bon Secours St. Francis is part of Bon Secours Mercy Health (BSMH), one of the 20 largest health systems in the United States and the fifth-largest Catholic health system in the country. The ministry’s quality, compassionate care is provided by nearly 60,000 associates serving communities in Florida, Kentucky, Maryland, Ohio, South Carolina, and Virginia, as well as in Ireland and the Philippines. Bon Secours Mercy Health provides care for patients nearly 14 million times annually through its network of more than 1,200 care sites, which includes 47 hospitals. In 2025, BSMH provided more than $600 million dollars in community investments across six states, ensuring cost is not a barrier to health care for our patients in need. Locally, Bon Secours St. Francis provides compassionate medical care to thousands of area residents through Bon Secours St. Francis Downtown and Bon Secours St. Francis Eastside, as well as a network of primary and specialty care practices, and ambulatory care sites across the Greenville region. The mission of Bon Secours St. Francis is to extend the compassionate ministry of Jesus by improving the health and well-being of our communities and bring good help to those in need, especially people who are poor, dying and underserved. For more information, visit BonSecours.com.