SOUTH CAROLINA – April 28, 2026 – NeuroSkye Therapeutics is a translational biotechnology company developing human BBB and blood-tumor-barrier (BTB) functional diagnostic platforms to inform treatment decisions in brain tumors. Operating at the intersection of neuro-oncology, precision diagnostics, and translational medicine, NeuroSkye addresses a critical gap in therapy selection by evaluating drug delivery feasibility across the BBB/BTB, enabling more informed, delivery-based clinical decision support and recurrence planning.
Solutions
NeuroSkye has developed a human, patient-derived BBB and BTB functional diagnostic platform designed to inform treatment decisions in brain tumors. The platform uses standardized human assembloid models to evaluate whether clinically relevant therapies can penetrate and persist across the BBB/BTB, providing delivery feasibility insight that complements existing molecular and imaging diagnostics.
By focusing on drug delivery as a prerequisite for efficacy, NeuroSkye aims to reduce treatment uncertainty and support more informed therapy selection and recurrence planning. The company is advancing the platform toward a CLIA-facing laboratory-developed test, with the long-term goal of integrating delivery-informed decision support into neuro-oncology workflows and clinical trial stratification.
Strengths
- Human-Relevant Modeling: NeuroSkye’s platform leverages patient-derived BBB and BTB assembloids built on over a decade of peer-reviewed academic research, providing a biologically relevant system to evaluate drug delivery in human brain tumor contexts rather than relying on animal or barrier-free models.
- Delivery-Focused Differentiation: Unlike genomics and imaging, which characterize tumor biology, NeuroSkye functionally evaluates drug penetration and retention across the BBB/BTB. This provides a complementary, delivery-focused layer of insight – addressing whether therapies can reach the tumor as a prerequisite for efficacy.
- Translational Design: The platform is engineered with standardized workflows, quality-control metrics, and reproducibility benchmarks to support progression toward a CLIA-facing laboratory-developed test rather than remaining a research-only model.
- Clinical Alignment: NeuroSkye is actively engaging clinicians and patient stakeholders to ensure its decision-support outputs integrate with tumor board workflows and address real-world treatment and recurrence planning needs.
Meet the Founder

Choi-Fong Cho, Ph.D. | Founder