DPX earns SBIR grant see more
DPX Technologies, a manufacturer of laboratory consumables for sample preparation, receives over $250,000 from the National Science Foundation (NSF) for a Small Business Innovation Research (SBIR) Phase I project. The project involves rapid purification of RNA and the development of fast detection for COVID-19.
RNA extraction is a key pre-analytical sample preparation step for viral RNA detection. Viral RNA detection is the current worldwide strategy used for early detection of the novel coronavirus SARS-Cov-2. The magnitude of the COVID-19 pandemic calls for unprecedented high throughput testing.
DPX Technologies has been developing sample preparation products for high throughput, automated methods for over a decade. Their patented and proprietary pipette tip technology harnesses the power of automated liquid handlers to provide solutions for a variety of applications. DPX was able to leverage the help and expertise of Tyler Tatum at 3Phase SC. “Tyler helped with navigating through all of the paperwork and rules. He was great to work with and extremely knowledgeable,” said William Brewer, CEO of DPX Technologies and principal investigator on the SBIR Award.
The South Carolina Department of Commerce Office of Innovation launched 3Phase in 2018 as a resource aimed at assisting research-based companies in South Carolina successfully acquire Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) awards. 3Phase provides training and workshops throughout the state on the federal SBIR and STTR programs, while managing the application process for a portfolio of companies, both at no cost to participants. The SBIR program funds early-stage research and development and is designed to provide equity-free funding. These investments stimulate technological innovation in the private sector, strengthening the role of small business in meeting federal research and development needs.*
* Excerpt regarding information on 3Phase program from South Carolina Department of Commerce website and https://www.3phasesc.com/
About DPX Technologies
DPX is committed to providing innovative sample purification solutions. We collaborate with our customers to provide the high-quality products they need for complex chemical and biological analysis.
Matt Bell named to head SC Launch see more
The South Carolina Research Authority (SCRA) has announced that Matt Bell was recently named Director of SC Launch and Executive Director of SC Launch, Inc. Bell replaces Russell Cook who resigned to focus on his recovery from a medical issue.
A member of SCRA’s leadership team, Matt Bell is responsible for leading the strategic direction of the SC Launch program, which provides mentoring, networking, and grant funding to eligible companies that are employing new technologies within the advanced materials and manufacturing, information technology, and life science sectors. He also serves as the liaison to the SC Launch, Inc. board of directors, which makes capital investments in SCRA Member Companies that successfully complete the due diligence process. Established in 2006, SC Launch, Inc., is an independent, nonprofit corporate affiliate of SCRA.
“Matt brings a broad background in startup creation from managing intellectual property and launching startups in academia to early-stage investing and venture capital experience. He is also an expert convener who understands how to bring the right people and resources to the table for economic development through innovation,” said Bob Quinn, SCRA Executive Director. “The SC Launch team has been accelerating the growth and success of Member Companies for many years, and Matt brings the right background and experience to lead this team as they guide our companies to becoming highly investible. We sincerely thank Russell Cook for his service to SCRA and the state, and we wish him a speedy and full recovery.”
Prior to coming to the SCRA, Bell was managing director for Discovery Partners Institute, a University of Illinois-led initiative that leverages the state of Illinois’ university resources to drive economic development through workforce training, student immersion, and research programs. He was also a managing director and a principal with Cultivian Sandbox Venture Fund where he raised capital, managed strategic investor relationships, and managed fund activities.
Matt Bell is a board member and advisor for Michigan State University’s state-wide, agriculture-focused translational fund, a former board member of Abcelex Technologies, and a U.S. Department of Agriculture Small Business Innovation Research grant reviewer. He earned a Master of Business Administration and a Bachelor of Science from the University of Illinois. He will be based in SCRA’s Greenville office.
Chartered in 1983 by the State of South Carolina as a public, nonprofit corporation, South Carolina Research Authority (SCRA) fuels South Carolina’s innovation economy through the impact of its four programs. SC Academic Innovations provides funding and support to advance multi-institutional, translational research and accelerate the growth of university-based startups. SC Facilities offers high-quality laboratory and administrative workspaces for technology-based startups and academic institutions. SC Industry Solutions facilitates and funds partnerships between and among startups, industry, and academia. SC Launch mentors and funds technology-based startups that may also receive investments from SCRA’s investment affiliate, SC Launch, Inc.
Executive Partnering, Virtual Exhibit Hall Add Draw for Power of Us Conference Feb. 16-17 see more
With conference registration surging more than 20% past prior record levels and the addition of a “singularly significant innovation announcement focused on cancer treatments and precision medicine advancement”, SCBIO's “The Power of Us” virtual conference Feb. 16-17 is preparing for its largest gathering ever next week... delivered virtually to registrants from across the Palmetto State plus 25 states and 8 countries.
Adding to the excitement is a just-scheduled “major innovation announcement” by a South Carolina company, in tandem with West Coast and German allies, that has significant implications for cancer diagnosis and treatment on a global level, organizers say.
Already in excess of 500 registrants from across America and around the globe, the acclaimed SCBIO conference – the annual gathering of South Carolina’s life sciences community – will also celebrate the rapid growth of the industry and the contributions of its 800+ organizations in helping America and the world overcome the brutal COVID-19 pandemic.
South Carolina life sciences has seen a doubling of firms and 40% increase in life sciences’ direct employment since 2017, which combine to make it the fastest growing industry sector in the state, according to recent data provided by Dr. Joseph Von Nessen, the state's research economist and noted economic development expert with the Moore School of Business at the University of South Carolina.
“Dr. Von Nessen’s data validates that the life sciences industry in South Carolina is experiencing stunning growth, thanks to the combined efforts of our state’s economic development teams, industry partners, research universities, elected officials and other partners,” said SCBIO CEO Sam Konduros. “It’s an exciting time to be a part of an industry that is saving lives and improving quality of care.”
The industry has a $12+ billion economic impact in the Palmetto State, with more than 800 firms located in 42 of 46 counties across the state and over 43,000 professionals employed directly or indirectly in research, development and commercialization of innovative healthcare, medical device, industrial, environmental and agricultural biotechnology products.
Organizers are tight-lipped about the Innovation Announcement details, which will be unveiled at 8:30 a.m. on the second day of the conference—February 17.
“We will say that the implications of the announcement include a new technology that has the ability to detect cancers at the earliest time ever, to further lifespans, and to unlock a new era of precision medicine, ” said Mr. Konduros.
Adding to the draw of the conference are scores of organizations from across America showcasing their capabilities in a virtual exhibit hall, direct 1-to-1 executive meetings on demand via a Partnering Portal, major industry awards and – naturally – top speakers.
Committed presenters include BIO Global CEO Dr. Michelle McMurry-Heath; Microsoft Vice President Jamie Harper, who leads the global team supporting higher education and K-12 initiatives; and Bill Stadtlander, Commercial Leader of Verily, the Google subsidiary focused on life sciences and use of health data and AI to improve lives.
Also speaking at SCBIO 2021 are Courtney Christian, Senior Director of Policy and Research at PhRMA and former leader of the Black Women's Health Imperative; Dr. Harris Pastides, former USC President and outgoing chair of the SC Institute of Medicine and Public Health; Dr. Pat Cawley, CEO of MUSC Health; and Dr. Marjorie Jenkins, Dean of the USC School of Medicine - Upstate and Chief Academic Officer of Prisma Health Upstate, among others.
Themed “The Power of Us,” the 2-day SCBIO 2021 virtual event will feature sessions on The Power of Innovation, The Power of Partnership, and The Power of People – each a fundamental force which drives the state’s surging $12 billion industry that is a key contributor to South Carolina’s expanding knowledge economy.
The conference will also feature SCBIO CEO Sam Konduros delivering the “State of South Carolina’s Life Sciences Industry” address, and release of SCBIO’s 2020 annual report.
Leaders already registered to attend include executives from Presenting Sponsor Vikor Scientific, Champion Sponsor Nephron Pharmaceuticals, Keynote Sponsor Medpoint, Pinnacle Awards Sponsor Softbox and others. Leading biotech and med-tech industry brands participating include BIO, Johnson & Johnson, AVX, PhRMA, AdvaMed, Poly-Med, VWR, Ritedose Corporation, Rhythmlink, ZEUS, Patheon Thermo Fisher, Zverse, Abbott, Alcami, SSOE – Stevens & Wilkinson, and more. All of South Carolina’s research universities – MUSC, Clemson and the University of South Carolina – are represented, as are major healthcare systems, the South Carolina Department of Commerce, SCRA, South Carolina Hospital Association and others.
Registration is open online at the 2021 Virtual Conference section of www.scbio.org. Registration is free to employees of most SCBIO investors and supporters as well as to students interested in life sciences careers, while faculty and teachers can attend the entire conference for $25. General admission tickets are available for as little as $75. Virtual Exhibit space and sponsorships are also available by inquiring at email@example.com.
For additional information on SCBIO or to register for SCBIO 2021, visit www.SCBIO.org.
Furman cited for excellence by global organization see more
Furman University’s Institute for Innovation and Entrepreneurship has been named an Outstanding Emerging Entrepreneurship Center by the Global Consortium of Entrepreneurship Centers, a group of more than 250 universities.
Other recipients of the 2020 award were Boston University, Eastern Washington University and Smith College. The centers, which had to have been nominated for the award within five years of launching, were judged on early success, engagement with stakeholders on and off campus, an established management team, novel or unique approaches and clearly established goals and objectives. Winners in recent years include Dartmouth College, Brown University, Vanderbilt University, Virginia Tech and Babson College.
“This recognition is a testament to Furman’s commitment to innovation and entrepreneurship and the unparalleled support by the campus community, alumni, parents, community members, administration and Board of Trustees,” said Anthony Herrera, executive director of Furman Innovation and Entrepreneurship. “In just two short years, we have built a globally recognized institute and paved a way for Furman to lead nationally among liberal arts and sciences universities in the space of innovation and entrepreneurship.”
According to Herrera, three strengths set Furman apart from other universities.
“Our engaged faculty and students from across disciplines; strong ties with the community, including city and state government organizations as well as local venture capital groups; and a core group of alumni and parents who provide financial support, make the effort self-sustaining,” he noted.
“This award signals that a liberal arts and sciences education can be a catalyst for innovation, that students who come to Furman can have a profoundly impactful experience as innovators and entrepreneurs regardless of their choice of major,” said Furman President Elizabeth Davis. “We are grateful that the Global Consortium of Entrepreneurship Centers recognized Furman’s role in creating an ecosystem of entrepreneurship for our students, faculty and the community.”
“The heart of innovation and entrepreneurship is creativity, in identifying opportunities and solving problems,” said Kem Wilson III ’98, a Furman trustee and alumnus, principal of Kemmons Wilson Companies and supporter of Furman Innovation and Entrepreneurship. “The entrepreneurial experience Furman students can experience will benefit them regardless of their career path.” Wilson’s grandfather founded Holiday Inn. The company that bears his name now manages a diverse portfolio of companies spanning a myriad of industries, from hospitality to green technology to consumer brands.
Furman Innovation and Entrepreneurship sprang from The Furman Advantage and its focus on self-discovery, engaging the community and experiential education. It launched in August 2018 with Herrera’s hiring and has become “a perfect vehicle to encourage cross-disciplinary thinking and provide students, faculty and community members a place to participate in engaged learning experiences,” Herrera said.
Early successes include:
- A pitch competition that attracted more than 80 student competitors and culminated in the most-attended pitch competition in South Carolina’s history; 530 people attending the final round between six students, where $30,000 in startup grants were awarded.
- The Summer Business & Innovation virtual boot camp that has attracted 42 students from 10 universities across the Southeast. Following the boot camp, the City of Greenville funded 10 student internships with local startup ventures.
- A virtual academy for high school students that led 62 teens from 11 states and 11 countries through a capstone project to pitch a venture in innovation and entrepreneurship, sustainability or community health.
- The “Class E Podcast,” produced in partnership with the Furman Department of Communication Studies, which presents biweekly talks and interviews with entrepreneurs, innovators and disruptors from the Furman network. Fourteen episodes have drawn more than 1,000 listeners.
- “Leading in Times of Crisis,” a series of six virtual workshops for corporate, entrepreneurial and nonprofit leaders that attracted more than 1,000 registrants.
- Collaborations, partnerships and ongoing relationships with organizations, including the City of Greenville, SCBIO, Upstate SC Alliance, Greenville Area Development Corporation, Build Carolina, Village Launch, NEXT, 6AM and VentureSouth.
In addition to continuing and expanding its programs, Furman Innovation and Entrepreneurship has extensive plans to become more engaged and integrated with Greenville, the Upstate and South Carolina. Herrera expects to make several announcements over the coming months about partnerships with corporate and community stakeholders.
MUSC Foundation for Research Development holds Vournakis NAI Induction Ceremony and Adm. Albert Baciocco Innovator of the Year ReceptionMUSC FRD honors innovators, patent recipients at virtual gala... see more
Congratulations to all of the honorees from the recent John N. Vournakis NAI Induction Ceremony and Annual Adm. Albert J. Baciocco Innovator of the Year Reception. Learn about teh honorees and this highly anticipated annual event right here!
KIYATEC Advancing Functional Ex Vivo 3D Cell Culture Models that Reveal Response Dynamics to Immuno-Oncology DrugsKey evidence to be presented at AACR 2020 see more
KIYATEC, Inc. today announced that it will present data at the 2020 American Association for Cancer Research (AACR) Annual Meeting, June 22-24, revealing how its 3D cell culture models characterize ex vivo tumor response and immunoreactivity to immune checkpoint inhibitors (i.e. PD-1, PD-L1 inhibitors) in solid tumors. These emerging capabilities address a significant unmet need in both preclinical drug development and clinical decision-making in oncology.
PD-1/L1 inhibitors have experienced meteoric growth over the last decade, offering hope to hundreds of thousands of cancer patients every year in the US alone. However, typically no more than 25-30% of eligible cancer patients who receive PD-1/L1 inhibitors actually respond to them. Given that the direct costs associated with PD-1/L1 therapy can run into the hundreds of thousands of dollars per patient, KIYATEC believes that pre-treatment, patient-specific PD-1/L1 response prediction could one day offer clinicians, patients and payers a more objective basis for determining PD-1/L1 inhibitor patient eligibility vs. today’s commonly used population-based biomarkers.
Evidence presented by KIYATEC at AACR 2020 will highlight findings of the company’s ability to detect dose-dependent response to checkpoint blockade and corresponding correlation with immune cell activation in high-throughput ex vivo 3D tumor spheroid models. KIYATEC believes these recent advances may represent key building blocks toward the eventual development and validation of clinical assays capable of accurate pre-treatment, patient-specific prediction of response to immuno-oncology drugs.
“We’re constantly innovating and expanding the capabilities of our 3D cell culture technologies to reduce the cost and risk of preclinical drug development for our immuno-oncology customers,” said Matthew Gevaert, CEO of KIYATEC. “As we continue to make these advances in immuno-oncology drug response on higher-throughput platforms, we can begin to envision a time when such capability would inform clinical decision-making for cancer patients as well.”
KIYATEC’s poster presentations at AACR 2020 are as follows:
- Abstract: 7397 / Poster: 315 / Session: 3D & Tissue Recombinant Models / June 22-24
Title: PARP inhibition in combination with pembrolizumab enhances cytotoxicity in ovarian cancer patient-derived 3D spheroids
- Abstract: 7132 / Poster: 2244 / Session: Immune Checkpoints 2 / June 22-24
About KIYATEC, Inc.
KIYATEC leverages its proprietary ex vivo 3D cell culture technology platforms to accurately model and predict response to approved and investigational cancer drugs targeting a spectrum of solid tumors. The company’s Drug Development Services business works in partnership with leading biopharmaceutical companies to unlock response dynamics for their investigational drug candidates across the majority of solid tumor types. The company’s Clinical Services business is currently engaged in the validation of clinical assays as well as investigator-initiated studies in ovarian cancer, breast cancer, glioblastoma and rare tumors, in its CLIA-certified laboratory. To learn more about KIYATEC, visit www.kiyatec.com.
Prisma Health, USC to collaborate on innovations see more
The University of South Carolina and Prisma Health – the state’s largest not-for-profit health organization – are announcing a partnership that aims to encourage the development and implementation of innovative health care delivery models, medical devices, digital health applications, and treatments for diseases.
Under the arrangement, which was approved by UofSC’s Board of Trustees on February 21, the University’s Office of Economic Engagement will assist Prisma Health – along with the UofSC Schools of Medicine in Columbia and Greenville – in identifying opportunities to develop mutually beneficial relationships with industry partners, bridging the gap between Prisma Health’s cutting-edge health research and the development of new technologies that help patients.
“At Prisma Health, we strive to go beyond treating diseases or their symptoms and aim to find cures and to design medical devices and digital capabilities that allow us to restore and transform lives,” said Mark O’Halla, President and Chief Executive Officer at Prisma Health. “Harnessing our expertise and that of the University of South Carolina together will help us accelerate our ability to address society’s most significant health challenges.“
Specifically, Prisma Health and UofSC will collaborate on a number of opportunities, including intellectual property patents and technology transfer support, operations development, cybersecurity, institutional insights, and strategic planning – all towards the shared goal of furthering research and innovation towards improving treatments and health care delivery. At its core, this partnership will drive innovation through UofSC’s extended successes delivering education, mentoring programs, and incubation asset development, as well as Prisma Health’s experience in leveraging its clinical and non-clinical expertise in the health care market, to drive innovations from benchside prototypes to clinical outcomes.
“This strengthens the outstanding partnership that already exists with Prisma Health. We are greatly committed to addressing the health needs of all South Carolina residents, and working together with Prisma in academics, research and patient care will make a real difference,” said UofSC President Bob Caslen.
As the state’s flagship university, UofSC is uniquely suited to help Prisma Health develop research or innovation partnerships that can lead to higher healthcare outcomes for patients across the state. This new relationship builds off of previous partnerships the university had with Prisma Health and its legacy predecessors, Greenville Health System and Palmetto Health, before they combined in 2019 to form Prisma Health.
“We have an extensive history of facilitating and supporting innovation efforts across multiple sectors,” said Bill Kirkland, executive director of UofSC’s Office of Economic Engagement. “Through this partnership with Prisma Health, we will now apply our commercialization and entrepreneurial successes to healthcare and life sciences. While this relationship will bear fruit for both insitutions, the real winners are the people of South Carolina, who stand to benefit from better access to care, innovative treatments, and the latest applications of research.”
“Prisma Health is committed to improving the health of South Carolinians,” said Brenda Thames, Prisma Health chief academic executive officer. “We are adapting to an ever-changing and increasingly challenging healthcare environment by becoming a learning health system that adopts rapid cycle innovation processes. While research provides the mechanism for evaluating and comparing the effectiveness of existing care models, innovation allows us to develop and improve new care models.”
Dr. David Cull, Prisma Health vice president of clinical and academic integration, added, “Through this partnership, we will create, test, and implement innovative initiatives that challenge the status quo and have the potential to reduce the cost of care, improve quality, and increase access to healthcare services.”
Commerce Office of Innovation introduces Scribble for the innovation community see more
COLUMBIA, S.C. - The S.C. Department of Commerce's Office of Innovation today announced the launch of Scribble - an online tool for the state's innovation community. Providing individuals and businesses a platform to access resources, this new site is designed to highlight South Carolina's exceptional ingenuity and create a common place for users to access a variety of helpful tools.
"South Carolina's burgeoning innovation sector has come a long way, and this new, state-of-the-art platform will ensure that entrepreneurs have all they need to thrive," said Secretary of Commerce Bobby Hitt. "Inspired by our human nature to document or write down that 'ah-ha' moment, we're excited to celebrate our innovators through Scribble."
With access to company video features, podcasts, blogs and events, Scribble allows users to create a profile to save resources and content, further enhancing the innovation community's connectivity. Launched at the 2019 DigSouth Tech Summit in Charleston, S.C., Scribble will help innovators connect with startup programs, venture capital and other resources around the state.
For more information, visit www.scribblesc.com.